In primates, considerable evidence accumulated in the past 15 years indicates that these operations involve the orbitofrontal cortex (OFC). IntroductionĮconomic choice entails computing and comparing the subjective values of different goods. Our results lay the foundations for a circuit-level analysis of economic decisions.
These groups match those previously identified in primates, except that the neuronal representation in mice is spatial (in monkeys it is good-based). Neuronal recordings revealed that different groups of cells encoded the values of individual options, the binary choice outcome and the chosen value. Optogenetic inactivation of LO dramatically disrupted choices by inducing erratic changes of relative value and by increasing choice variability. Choice patterns closely resembled those measured in primates.
In the experiments, mice chose between different juices offered in variable amounts. Here we present a mouse model of economic choice behavior, and we show that the lateral orbital (LO) area is intimately related to the decision process. Conversely, previous work in rodents provided conflicting results. Evidence from primates indicates that this behavior relies on the orbitofrontal cortex. Please ensure you have registered your company, failing which any quotations submitted will unfortunately not be considered until such time as the legislation has been adhered to.Īs an entity of the eThekwini Municipality, uShaka Marine World is committed to stamping out fraud and corruption.Economic choices entail computing and comparing subjective values. Failing to register on the National Treasury’s database will result in your business being non-compliant with the legislation and as a consequence will not be permitted to transact with eThekwini Municipality.Īfter successfully registering on the Central Supplier Database, suppliers are to ensure that they are also registered on the eThekwini Vendor Portal on and must ensure that all supporting documentation is provided. In compliance with the Municipal Finance Management Act (MFMA), No 56 of 2003 and its Municipal Supply Chain Management Regulation 14, eThekwini Municipality hereby requests all suppliers of goods and services are to apply to be registered on its supplier database via National Treasury’s Centralised Supplier Database.
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